Frank LiuPhD/MBA, General Manager
Comprehensive work, Formulation development and industrialization
Professional Titles & Affiliations:Deputy Director, Pharmaceutical Preparation Specialty Committee and Pharmaceutical Excipients Specialty Committee, Guangdong Pharmaceutical Association; Drug Registration and Review Expert, Guangdong Provincial Medical Products Administration (GDMPA); Master's Supervisor (Bioengineering), South China University of Technology (SCUT).Experience & Expertise:Possesses over 30 years of experience in pharmaceutical formulation R&D, industrialization, and enterprise management in both the US and China. Specializes in the development and industrialization of complex drug delivery systems, including: sustained/controlled release formulations, nanoformulations, long-acting injectables (LAI), delivery carriers/vectors. Expertise in the design, development, and industrialization of biodegradable excipients for long-acting formulations. Key achievements include:globally pioneering development and industrialization of ReGel®, a thermosensitive biodegradable hydrogel. Development and industrialization of copolymers: mPEG-PLLA (methoxy polyethylene glycol-poly(L-lactic acid)), PLGA (poly(lactic-co-glycolic acid)), mPEG-PLGA, and PLGA-PEG-PLGA.Product Development Track Record:Has led or contributed to the development of over 30 commercialized products and over 10 clinical-stage products. Notable examples include: globally pioneering development of Paclitaxel Nanomicelles (marketed in the EU and South Korea; phase III clinical trials in the US).Development and industrialization of OncoGel®, the world's first Paclitaxel-loaded thermosensitive hydrogel (phase III clinical trials in the US).Globally pioneering development and industrialization of a sustained-release tablet for heart failure (anti-HF) (class I Innovative Drug; phase III clinical trials).